Clearwater, FL - (727) 462-5582
Beverly Hills, CA - (310) 975-7033

Rush Researchers Use Stem Cells to Repair Damaged Knee Cartilage


Rush University is conducting the first clinical trial using Cartistem.

Cartistem is a Mesenchymal stem cell derived umbilical cord blood (allogenic or donor) tissue that has been expanded to greater numbers. The stem cells are then mixed with hyaluronan, then surgically administered via arthroscopic surgery following microfracture (a drilling into the bone technique that involves considerable downtime).

This study will be a two-year, two-phase study with 12 participants ages 18 and older with body mass index less than 35.

Dennis M. Lox, MD,, a Sports and Regenerative Medicine Specialist in the Tampa Bay, Florida area, comments that this is not the first study to use allogenic or donor stem cells. Studies prior to the Rush one have used adult cells. Dr. Lox notes that when cells are cultured and expanded to greater the cell division of obtaining greater numbers the cells age significantly. This will make the umbilical cord cells the age of a young adult, as opposed to adult cells that age to elderly cells.

Dr. Lox states this may not fix some of the other problems associated with expanding stem cells. This study with umbilical cord cells, even if ever approved, will be years away, and may ultimately prove to not be as effective as using the patients own cells without expansion in a lab. Another problem arises in the form of a question: what about future diseases for which umbilical cord stem cells carry an undetectable gene? These would include diseases that develop in adult life like MS, ALS, autoimmune diseases like Rheumatoid Arthritis or even cancer.

There are unknowns to using donor tissue that could not be answered then for 20-30 years. For now its safer to use your on stem cells and treat early Dr. Lox comments. Arthritis is a progressive joint issue that if treated early the prospects of progression can be addressed.

Dennis M. Lox, MD, serves patients in the greater Tampa Bay area, including, Clearwater, St. Petersburg, Tampa, New Port Richey, Sarasota, Orlando and Spring Hill. He has been pleased to accommodate the needs of patients throughout Florida, the United States, the Western Hemisphere, and Europe, as well. Located in the 33765 area, our office can be reached at (727) 462-5582.

About Dennis M. Lox, M.D.

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.

Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.

Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

Are You Looking to Avoid Surgery?

If you haven't found joint relief should schedule a personal consultation with Dennis M. Lox, M.D., to learn if you are able to get joint relief without the need for invasive surgery.

Stem Cell Therapy in Clearwater, FL and Beverly Hills, CA

Dr. Lox treats the Tampa Bay Metro Area including Clearwater, St. Petersburg, Tampa , Pinellas Park, Palm Harbor, Orlando and Sarasota as well as the Los Angeles Metro Area including Santa Monica and Beverly Hills.

Call our office in Clearwater, FL or Beverly Hills, CA to schedule a consultation with Dr. Dennis Lox.

Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

Beverly Hills, California Office

450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

© 2019, All Rights Reserved, Dennis M. Lox, M.D. - Privacy Policy - About Us

*DISCLAIMER: Like all medical procedures, those performed by Dennis Lox, M.D. have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.