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Osteonecrosis of the Ankle Dr. Lox

Osteonecrosis of the Ankle Treated with Stem Cells. Osteonecrosis also referred to as avascular necrosis (AVN), is a condition in which the blood supply to a region of bone is disrupted, leading to bone cell death or necrosis.

Osteonecrosis most frequently is seen in the hip joint, however, it may occur in any joint including the ankle. Osteonecrosis or AVN has been treated with stem cell therapy as an option to traditionally recommended surgeries such as ankle fusion or joint replacement.

The use of stem cells has seen increasing usage in the treatment of osteonecrosis or avascular necrosis (AVN), as more attention has been given to alternative treatment modalities. Patients were previously given little choice except to consider irreversible surgery procedures like ankle joint fusion or ankle joint replacement. Unlike the more common knee and hip joint replacement, ankle joint replacement is difficult and failure rates are higher, making recommendations for ankle fusion more common. When osteonecrosis or AVN occurs in the ankle, it may involve the shin bone or tibia, the ankle bone or talus, or a combination of these bones. Osteonecrosis often leads to accelerated joint breakdown which is the most feared consequence of the diagnosis of avascular necrosis.

When the necrotic portion of bone collapses this leads to a rapid secondary joint degeneration. This is the most frequent reason patients are told they need an ankle joint replacement or ankle fusion. Alternatives such as stem cell injections allow patients to defer or avoid these surgical procedures. This is a desirable measure especially in younger patients or those who are athletes. Ankle fusion will end most athletic careers. The ability to consider stem cell therapies for ankle osteonecrosis (AVN), can provide these younger patients or athletes with the ability to delay these surgical procedures to a more appropriate age. The effects of ankle fusion or joint replacement in younger patients have profound implications for their quality of life as they age. Ankle osteonecrosis may be seen in one leg especially after trauma, or in both legs if there is an underlying process that affects the bone in a systemic or no n-traumatic fashion. Stem cell therapy may be a viable option for patients diagnosed with ankle osteonecrosis.

If you’re in pain or had an injury and are looking for an alternative to surgery, contact us immediately at one of our locations. Our Main Medical Center located in Tampa Bay, Florida (727) 462-5582 or at Beverly Hills, California (310) 975-7033.


About Dennis M. Lox, M.D.

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.

Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.

Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

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Orthobiologics in Tampa Bay, FL and Los Angeles, CA

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Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

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450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

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