Clearwater, FL - (727) 462-5582
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Preiser’s Disease (AVN of the Scaphoid): a Leading Hand Surgeon From India Consults Dr. Dennis Lox For a Rare Form of Avascular Necrosis (AVN)


Tampa, Saint Petersburg and Clearwater, FL

Preiser’s Disease is non-traumatic AVN of the scaphoid which is a rare occurrence. Post- traumatic AVN of the scaphoid bone, especially after fracture is not uncommon. Preiser described this condition in 1910. Yet all of Preiser’s cases were associated with trauma or fracture, therefore he was more apatly describing post-traumatic scaphoid AVN. True non-traumatic or idiopathic scaphoid AVN appears infrequently in the medical literature and therefore is a rare form of AVN. Avascular necrosis (AVN) also referred to as Osteonecrosis develops when the blood supply to a region of bone becomes disrupted leading to bone cell death (necrosis). In the case of the scaphoid, blood supply is derived from the lateral and distal branches of the radial artery.

This occurs by dorsal and palmar branches. The dorsal branch is highly variable, and the proximal portion is often left with little support. It may be overlooked on x-rays early on.  If the scaphoid becomes necrotic it may collapse and affect wrist mobility, as the scapho-lunate articulation is important in stability of the first carpal row. Stem cells have been utilized for treatment of AVN. Stem cells may not only repair bone cells (osteocytes), but are involved in angiogenesis (the formation of new blood vessels). Therefore, stem cells may be a viable treatment option for scaphoid AVN, if the joint integrity is still maintained. After the joint collapses, rapid secondary degeneration occurs.

The use of Regenerative Medicine procedures such as Platelet Rich Plasma (PRP), Stem Cells, and Cytokines all may play an important role in the treatment of AVN.

Dennis M. Lox, M.D., serves patients in the greater Tampa Bay area, including, Clearwater, St. Petersburg, Tampa, New Port Richey, Sarasota, Orlando and Spring Hill. He has been pleased to accommodate the needs of patients throughout Florida, the United States, the Western Hemisphere, and Europe, as well. Located in the 33765 area, our office can be reached at (727) 462-5582.

About Dennis M. Lox, M.D.

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.

Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.

Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

Are You Looking to Avoid Surgery?

If you haven't found joint relief should schedule a personal consultation with Dennis M. Lox, M.D., to learn if you are able to get joint relief without the need for invasive surgery.

Stem Cell Therapy in Clearwater, FL and Beverly Hills, CA

Dr. Lox treats the Tampa Bay Metro Area including Clearwater, St. Petersburg, Tampa , Pinellas Park, Palm Harbor, Orlando and Sarasota as well as the Los Angeles Metro Area including Santa Monica and Beverly Hills.

Call our office in Clearwater, FL or Beverly Hills, CA to schedule a consultation with Dr. Dennis Lox.

Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

Beverly Hills, California Office

450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

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*DISCLAIMER: Like all medical procedures, those performed by Dennis Lox, M.D. have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.