The Many Causes Of Avascular Necrosis (AVN): Dr. Lox Discusses
Avascular necrosis (AVN) occurs from a variety of causes. Dr. Lox sees many patients with AVN for evaluation of stem cell therapy. Avascular necrosis also referred to as osteonecrosis, occurs when the blood supply to a region of bone becomes impaired leading to necrosis or bone cell death. The hip is most frequently encountered, followed by the shoulder, then the knee. Stem cells are becoming a viable treatment option for AVN.
The most frequent cause of AVN is trauma. Trauma may result in disruption of blood flow by shearing of blood vessels such as in fracture and dislocations, or by minute changes to blood flow as the result of trauma. Obviously, the greater the degree of trauma, the greater the propensity for ischemic changes and necrotic lesions of bone.
Spontaneous Osteonecrosis or Avascular necrosis occurs without a known precipitous factor. There may still be a cause that has yet be identified or never be found.
Medical conditions also are associated with an increased risk of AVN. Dr. Lox has seen nearly every risk factor, including some of the more rarely noted conditions. Dr. Lox an expert in Sports and Regenerative Medicine has utilized stem cell therapy for many of these conditions.
Radiation and Chemotherapy
Autoimmune disorders (RA and Lupus)
Excessive Alcohol consumption
Caisson’s disease (decompression sickness)
Sickle cell disease
Not all are isolated events. For instance, Lupus may be treated with high dose corticosteroids on a repetitive basis. Dr. Lox has seen a ballet dancer with repetitive trauma, sickle cell trait, and severe asthma treated numerous times with intravenous corticosteroids.
AVN is often complex, and discussion of using Regenerative Medicine procedures such as Platelet Rich Plasma ( PRP) and Stem Cell Therapy should be done with an experienced expert in this field.
About Dennis M. Lox, M.D.
Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.
Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.
Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.