Patient with Knee Arthritis From Los Angeles, California
Knee Arthritis Is Common
When a patient from (LA) Los Angeles, California consulted Dennis M. Lox M.D. for his knee pain, he was surprised learn it was true. This patient from knee arthritis was only 42. He thought knee arthritis was something you only got when you were older.
After a lengthy consultation with Dr. Lox, he had a totally different perspective. Knee arthritis, or more properly termed degenerative knee osteoarthritis, can be multi-factorial.
He was an ex-Basketball player and football player in high school, with a significant knee injury in high school while playing football. He tore his Anterior Cruciate ligament (ACL), his medial meniscus, and medial collateral ligament.
These three injuries, are termed the terrible triad in Sports Medicine. This is because it is not just painful, but a very violent injury to the knee joint. Just the anterior cruciate ligament (ACL) tearing, has ended many an athletes sports career.
An understanding of knee degenerative arthritis progression over time, has shown trauma and surgery, accelerates knee degenerative arthritis progression over time. Therefore, the more significant the trauma the faster the progression of knee arthritis typically develops.
Knee arthritis is second only to spine or back arthritis in frequency. Thus, knee arthritis is a common entity, not just confined to older age people.
Can We Alter Knee Arthritis Progression?
This is what all the research has been focusing on for decades. Much with complete failure. The pharmaceutical industry was enamored with arthritis non-steroidal anti-inflammatory medications (NSAIDS) for decades.
Producing new varieties for years. These are the ibuprofen and naproxen type of class medicines. Many doctors still prescribe these, despite the fact that highly academic medical associations, such as The American Academy of Rheumatologists, The International Cartilage Repair and Regenerative Society, and The American Academy of Orthopedic Surgeons, all have stated there is no place for the long term usage of these medications, for the treatment of degenerative arthritis.
Unfortunately, the large machinery of the medical system just keep doing busy as usual. This also true of corticosteroids (cortisone) injections for knee arthritis, and hyaluronic acid injections. Nothing supports these medications or injections, stop arthritis knee progression.
Yet they are still commonly done with lack of efficacy over time. Cortisone injections, may provide short term anti-inflammatory relief for knee pain, but nothing lasting.
The same is true of knee hyaluronic acid injections. They do not alter knee arthritis progression. Large studies have shown only about a third of patients get short term relief, which means two thirds or 66% of people who get hyaluronic acid injections derive no benefit in pain relief.
This again is why such highly regarded scientific medical and research societies as The International Cartilage Repair and Regenerative Society, have deemed it’s use in knee degenerative arthritis as not an effective treatment.
What About Regenerative Medicine, Stem Cells and Arthritis Progression?
This is where the best science and most exciting research lies.
Regenerative Medicine is the field of medicine that encompasses Stem Cells, Biologics, and Tissue Engineering.
There has been abundant research in the animal model, showing stem cells can not only regrow cartilage, but prevent its development when treated early.
That becomes a problem with human research.
The therapeutic window for optimal prevention of arthritis, in a post traumatic injury model has long passed, before seeking Regenerative Medicine and stem Cell Therapy treatment options are considered.
Not so with animal studies, where treatment can be uniformly done a week after an experimental induced knee trauma is done. So much fascinating Regenerative Medicine discoveries are old, yet still not mainstream due to problems with our health care system.
In 2009, Dr. Steve Badylak, was featured on the news program 60 minutes for regrowing injured soldiers quadriceps muscles from IED explosive injuries. This treatment was done as opposed to amputation.
Earlier work, resulted in regrowing severed fingers, including the finger print. This is still being done by some physicians for finger regrowth, yet amputation is more cost effective for larger wounds. So for the naysayers to say we cannot regrow cartilage, they simply don’t know the research in the field of Regenerative Medicine.
We can regrow cartilage.
There are many differences when dealing with humans, as opposed to the animal model. Younger is easier because there is typically less knee arthritis.
However, so many factors are important to consider when evaluating patients. Weight, diet, prior injuries and knee surgeries, in addition to the degree of knee arthritis.
When you are 75 with knee arthritis, there is no miracle stem cell to make your knee 18 again. However, goals such as decreased knee pain, improved walking,and functional life are realistic goals for many patients.
Dr. Lox has treated many athletes who stay extremely active in highly intense sports in their 60’s with knee arthritis after Regenerative Medicine Stem Cell Therapy. Marathoners, IRONMAN Competitors, Senior Tennis Circuit Players to name a few. So there are no hard fast roles.
Personalized Regenerative Medicine for the Patient With Knee Arthritis
Dennis M. Lox M.D., believes in a personalized medicine approach to each patient with knee arthritis. Everyone is different. There is no one size fits all treatment approach for everyone.
A teen athlete, is not a 60 year old athlete. A 99 year old patient, is not a 69 year old.
Longevity genes are a good thing for patients to have, yet even with longevity genes, diseases can occur. Cancer chemotherapeutic treatment has an impact on the cellular level. Everything is important to the experienced expert in Regenerative Medicine.
This is why Dr. Lox firmly believes in a personalized approach to Regenerative Medicine. Dr. Lox practices Sports and Regenerative Medicine in the Tampa Bay, Florida area, and in Beverly Hills, California.
About Dennis M. Lox, M.D.
Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.
Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.
Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.