Osteonecrosis or Avascular Necrosis (AVN) and Stem Cell Treatment

Osteonecrosis or Avascular Necrosis (AVN) and Stem Cell Treatment

Stem cells for the treatment of Osteonecrosis or Avascular necrosis (AVN) may be a viable treatment option. Surgery carries potential complications with AVN, including loss of joint mobility and failure of joint replacement. Fused joints such as the wrist or ankle may seriously affect daily living and end a sports career. Many commonly replaced joints such as the hip and knee, are also difficult if the surgery is unsuccessful or in younger patients.

What is Osteonecrosis or Avascular Necrosis?
Osteonecrosis and Avascular necrosis are synonyms, with slight name variations yet both reflecting the same underlying pathophysiology.
Osteo- Bone
Necrosis- Cellular Death
Avascular- loss of vasculature (avascularity)

Causes of Osteonecrosis
Trauma
Spontaneous or insidious
Excessive Corticosteroids (cortisone)
Excessive Alcohol
Radiation therapy
Chemotherapy
Lupus
Sickle Cell Disease
Decompression sickness

Regenerative Medicine Strategies
Platelet Rich Plasma (PRP)
Stem Cell Therapy

Platelet Rich Plasma (PRP) is a concentrated source of platelets which has a rich supply of growth factors which may aid in certain aspects of repair.

Stem Cell Therapy provides precursor cells that can become new bone and cartilage cells, as well as function as a powerful immumodulator, suppressing inflammation.

Dennis M. Lox, MD, is an expert in Sports and Regenerative Medicine. Dr. Lox has utilized PRP and Stem Cell Therapy for Osteonecrosis or AVN.