Clearwater, FL - (727) 462-5582
Beverly Hills, CA - (310) 975-7033

Knee AVN with Lupus

A patient with Lupus was treated with numerous systemic Rheumatologic medications, including corticosteroids. She was referred to Dr. Dennis Lox M.D. an expert in Sports and Regenerative Medicine, with special expertise in the treatment of AVN or Avascular necrosis. Both knees were affected. There was no joint collapse, and she wanted to avoid total knee replacement surgery, as she was 34, and a young mother.
Dr. Lox agreed on Regenerative Medicine, a d Stem Cell Therapy was a good alternative to knee replacement surgery.

Avascular Necrosis

Avascular necrosis abbreviated as AVN, is also commonly referred to as osteonecrosis. It may also be called aseptic necrosis, bone infarction, or ischemic necrosis. They all refer to the same disorder.
AVN or Osteonecrosis occurs when the blood supply to a region of bone becomes impaired or compromised. This leads to bone cell death or necrosis.
The hip is the most commonly affected joint, followed by the shoulder, then the knee, however AVN can occur almost anywhere. AVN may be seen in multiple joints. Both hips are common, but it may occur in a hip and a knee, or other presentations, such as a hip, knee, and ankle. An expert in the evaluation and treatment of AVN must be alert to the possibility of unusual presentations of AVN in patients with multiple joint complaints. These are typically associated with high-risk factor causative factors such as excessive corticosteroid use.

Why Do Some People Get AVN?

Trauma is the leading cause of AVN. The hip is most frequently seen.
Following trauma, Idiopathic or unknown cause is the next leading cause.
Idiopathic is troubling, as most people want a reason, and before assigning the diagnosis of idiopathic or unknown cause, all other potential causes must be excluded.
Other Associated Factors of AVN
Excessive Corticosteroids
Rheumatologic diseases Such as Lupus or Rheumatoid Arthritis
Sickle Cell Trait
Chemotherapy
Radiation therapy
Vasculitis
Lipid Storage Diseases
AIDS
Decompression sickness
Excessive Alcohol

Regenerative Medicine and Stem Cell Therapy

Dr. Lox is often asked to consult or treat patients with AVN or Osteonecrosis. These patients are often looking for alternatives to surgery. Knee replacement surgery, hip replacement surgery, shoulder replacement surgery, or ankle fusion. This is especially true in young patients and athletes. Joint replacement surgery can often end a sports career, and in young patients, the concern is the joint replacement surgery will wear out due to their young age.
All these factors make Regenerative Medicine and Stem Cell Therapy more appealing as it is non-surgical, and preserves options down the road. Surgery can not be reversed.
Patients are often motivated by utilizing their own bodies to repair cells to try and heal themselves. This is the cornerstone of Regenerative Medicine and Stem Cell Therapy.


About Dennis M. Lox, M.D.

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.

Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.

Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

Are You Looking to Avoid Surgery?

If you haven't found joint relief should schedule a personal consultation with Dennis M. Lox, M.D., to learn if you are able to get joint relief without the need for invasive surgery.

Stem Cell Therapy in Clearwater, FL and Beverly Hills, CA

Dr. Lox treats the Tampa Bay Metro Area including Clearwater, St. Petersburg, Tampa , Pinellas Park, Palm Harbor, Orlando and Sarasota as well as the Los Angeles Metro Area including Santa Monica and Beverly Hills.

Call our office in Clearwater, FL or Beverly Hills, CA to schedule a consultation with Dr. Dennis Lox.

Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

Beverly Hills, California Office

450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

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*DISCLAIMER: Like all medical procedures, those performed by Dennis Lox, M.D. have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.