Clearwater, FL - (727) 462-5582
Beverly Hills, CA - (310) 975-7033

Dr. Lox on AVN New Treatments with Regenerative Medicine

Video names
The greatest development in the treatment of avascular necrosis (AVN) in the last decade or for that matter ever has been the understanding of the role that Regenerative Medicine, Stem Cells, and Tissue Engineering has had on the potential treatment options and scientific breakthroughs that may continue to occur as the result of this technology.

Avascular Necrosis What’s in The Name?

Avascular Necrosis abbreviated AVN essentially means:
-Avascular or loss of blood flow to a region
-Necrosis or bone cell death
-AVN is often called by other names especially in other countries, most commonly Osteonecrosis.
Other names used for AVN are aseptic Necrosis, bone infarction.
AVN can sometimes refer to A specific bone with a different name.
Avascular Necrosis
Avascular Necrosis
Just to add a little more confusion to the term Avascular Necrosis specific names of the bone involved may be used, often the name of the first physician who described the condition.


Disease States that May Predispose to AVN or Osteonecrosis

Certain disease states may predispose to the development of AVN. Treatment of these, or recognizing the associated risk factors or treatments used that may induce AVN, are paramount to not just understanding AVN, but helping treatment, and minimizing new development of bone necrosis.

Video perinatal

Regenerative Medicine and Stem Cell Options with AVN or Osteonecrosis

There are many patients looking earlier to Regenerative Medicine and Stem Cell Therapy as options. Before often there were given either get a joint replacement surgery or fusion or wait till it is bad enough. These answers are not satisfactory to proactive patients, parents, and especially athletes.  With many famous name professional athletes having stated they opted for Regenerative Medicine and Stem Cell Therapy, there is less of a stigma or fear of the unknown now compared to 10 years ago. Dennis M. Lox M.D. is an expert in Sports and Regenerative Medicine and has seen the changes in the last decade. It not as much advancement in what we do, it is more knowledge of what the stem cell can or cannot do. Some old assumptions that more stem cells were better if cultured to higher yields, did not bear out in long term studies. Additionally, we know the homing capacity of stem cells is impaired by multiple cell divisions in a lab. It is wise to stay with the same day, the same person FDA rule as its not just smart scientific-based medicine, it’s the rules. Anything outside the same day is not the practice of medicine, it falls into the realm of drug therapy. Thus it must be approved as a drug.  Perinatal Tissue’s Placenta, Amniotic, Cord Blood, Umbilical tissue are labeled by the FDA as medical devices, not as approved drugs. This is because if it were a pure stem cell product it would fall into the category of being approved as a drug, which they are not. There are presently two cord blood hematopoietic drugs approved for use in specific conditions. The many center’s confusing patients tissue types younger is better, or placental, amniotic, or any other perinatal tissue are just misinforming patients. Dr. Lox has lectured twice at the International Perinatal Society Meeting once in Aspen, and once in Teaneck, New Jersey.  The purpose was a future view from Dr. Lox’s perspective on perinatal cells of drug origin, combined in some cases with the patients own cells for sports medicine.  Dr. Lox’s expertise in both fields was used to spark discussions of the future.  This has nothing to do with tissue grafts approved for wound therapy as medical devices. This is where the continued propagation of misinformation to patients continues to occur by multiple parties that either doesn’t know, or ignore the difference, and misinformation to patients occurs. It is important to know a Regenerative Medicine specialist true credentials.


Tampa Bay Metropolitan Area, Florida (727) 462-5582

Los Angeles Metropolitan Area, Beverly Hills, California (310) 975-7033

About Dennis M. Lox, M.D.

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.

Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.

Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

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Stem Cell Therapy in Clearwater, FL and Beverly Hills, CA

Dr. Lox treats the Tampa Bay Metro Area including Clearwater, St. Petersburg, Tampa , Pinellas Park, Palm Harbor, Orlando and Sarasota as well as the Los Angeles Metro Area including Santa Monica and Beverly Hills.

Call our office in Clearwater, FL or Beverly Hills, CA to schedule a consultation with Dr. Dennis Lox.

Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

Beverly Hills, California Office

450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

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*DISCLAIMER: Like all medical procedures, those performed by Dennis Lox, M.D. have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.