Dennis M. Lox, MD, a Sports and Regenerative Medicine Specialist has treated his share of difficult cases. Avascular necrosis (AVN) also referred to as ischemic necrosis and osteonecrosis, occurs when the blood flood flow to the bone is disrupted leading to bone cell death (necrosis). The problem with this is that if the necrotic zone collapses, it leads to rapid secondary osteoarthritis (joint destruction). The leading cause of AVN is trauma. Many famous athletes have had avascular necrosis of the hip (Bo Jackson and Brett Favre). Bo Jackson never played professional football again after he was tackled and injured his hip. Favre was lucky, secondary arthritis never set in, and his avascular necrosis of the hip remained stable. Despite occasional hip pain.
The prognosis for Brett Favre is eventual osteoarthritis of his hip. The utility of stem cells in the management of Avascular Necrosis (AVN) is multifold. Acute effects are aimed at increasing blood flow through angiogenesis. Secondly, the stem cells may produce new bone cells via differentiation, thirdly, the stem cells may exert a positive effect on the joint, preventing secondary osteoarthritis. All three combined is excellent. Yet, just preventing secondary arthritis may be enough to keep a patient function and prevent a total hip joint replacement.
When a patient presents with hip AVN, all these considerations are weighed and measured. It is through such an approach that optimal outcomes occur.
Dennis M. Lox, MD, serves patients in the greater Tampa Bay area, including, Clearwater, St. Petersburg, Tampa, New Port Richey, Sarasota, Orlando, and Spring Hill and can accommodate the needs of patients throughout Florida, the United States, the Western Hemisphere, and Europe, as well. To learn more about stem cell therapy and other regenerative services offered by Dr. Lox, call (727) 462-5582.