Tampa Bay, FL - (727) 462-5582
Beverly Hills, CA - (310) 975-7033

A North Carolina Woman with Lupus, AVN Hips, now AVN Shoulder

AVN is complicated enough, adding Lupus, Rheumatoid arthritis, long term corticosteroid usage, and multi-joint AVN to the equation makes it far more complicated. Especially when both hips have been replaced due to advanced AVN, and now the AVN is in the shoulders. This is the history a 46-year-old North Carolina woman gave to Dr. Lox. Not an easy story, but nothing new to Dr. Lox.

The Problem with Systemic Associated AVN

hip avn

Trauma is the leading cause of AVN or avascular necrosis. Next is idiopathic or unknown, following that are many systemic associated factors such as excessive Corticosteroid usage and Autoimmune disorders like Lupus and Rheumatoid Arthritis. Dennis M. Lox M.D. is a Sports and Regenerative Medicine expert, with special expertise in AVN. Dr. Lox has treated many Autoimmune-associated AVN cases, however, Dr. Lox notes that an overwhelming number have been treated with excessive Corticosteroids. This makes understanding cause and effect difficult, as many Rheumatologists continue to treat the Autoimmune flares of Lupus or RA with corticosteroids. It may be that the corticosteroids were the underlying culprit all along. Some of the Autoimmune disorders are associated with vasculitis which can indeed cause impaired blood flow to the bone. However, vasculitis is not seen in all these autoimmune cases with AVN. Avascular necrosis is sometimes referred to as osteonecrosis. AVN occurs when the blood supply to a region of bone is impaired leading to bone cell death. Corticosteroids may affect the blood flow directly at the bone blood vessel interface.

When Hips and Shoulders both Have AVN

Systemic AVN as opposed to traumatic AVN may occur in multiple areas and may show up at different time intervals. Making it almost like a ticking time bomb, once it has been diagnosed in one area.  This patient was diagnosed with AVN of both hips and shoulders.  The AVN was first diagnosed after continued hip pain for several months. There was no trauma. An MRI revealed AVN of both hips. She eventually had hip replacement surgery to both hips 3 years ago.  This year she began having pain in both shoulders. Her right shoulder was worse than her left shoulder, and she is right hand dominant, so it was more troublesome for her. This led to her eventually having MRI’s of both shoulders.  Right-handed rotator cuff frayed supraspinatus tear, a small focal area of AVN.  Right shoulder much more pain than left.  Left small well-defined area of AVN superior femoral head no collapse no moderate pain.  She is now on biologics, she was intermittently given high doses of corticosteroids when she had flare-ups of her Lupus or RA for up to 6 months at a time. She has stopped taking the steroids since her diagnosis of AVN.  After having both hips replaced in 2016, and her recent diagnosis of shoulder AVN, she doesn’t want a total shoulder replacement, so she researched Regenerative Medicine and Dr. Lox.

Dr. Lox has treated nearly every type of risk factors for AVN and nearly every joint.  The experience has allowed him to advise young athletes, professional athletes with AVN, and patients from all age groups with systemic associated AVN affecting multiple joints.

Tampa Bay Metropolitan Area, Florida 727-462-5582

Los Angeles Metropolitan Area, Beverly Hills, California 310-975-7033


About Dennis M. Lox, M.D.

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help.

Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment.

Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

Is Regenerative Medicine Therapy Right For You?

People who haven't found meaningful pain relief should schedule a personal consultation with Dennis M. Lox, MD, to learn if innovative regenerative medicine therapy can be beneficial.

Dr. Lox Provides Stem Cell Therapy in Tampa Bay, FL and Los Angeles, CA

Call our office in Clearwater, FL or Beverly Hills, CA to schedule a consultation with renowned sports and regenerative medicine specialist Dr. Dennis Lox. Find out how you can experience pain relief and get back to your daily life with the help of innovative and customized cutting-edge treatments.

Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

Beverly Hills, California Office

450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

*DISCLAIMER: Like all medical procedures, those performed by Dr. Dennis Lox have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Dennis M. Lox, M.D.

Sports & Regenerative Medicine Centers

Conditions Treated

We specialize in helping people find relief without the need for surgery.

© 2019, All Rights Reserved, Dennis M. Lox, M.D. - Sports and Regenrative Medicine Centers