Clearwater, FL - (727) 462-5582
Beverly Hills, CA - (310) 975-7033

Knee AVN doing well after Stem Cell Therapy

A year after stem cell therapy for knee AVN, the patient is doing very well. This patient noted diminished pain, improved function and walking.

Knee Pain

Knee pain is a common orthopedic problem. Avascular necrosis (AVN) occurs when the blood supply to a region of bone becomes impaired. This loss of blood supply results in ischemia leading to bone cell death or necrosis. This is commonly called avascular necrosis (AVN), though many other names have been used to describe the same condition.

AVN has been also called osteonecrosis, ischemic necrosis, aseptic necrosis, and bone infarction. AVN is most commonly seen in the hip, followed by the shoulder, then the knee joint. AVN may be seen in one joint or multiple joints depending upon associated or causative factors. The hip is the most common joint to be seen bilateral or in both hips. It can also present as hip and knee involvement, or multiple other joints.

AVN Causes

Trauma is the leading cause of knee AVN. Another leading cause of AVN is idiopathic or unknown etiologies. Other associated or causative factors include excessive corticosteroids (cortisone), autoimmune disorders (Lupus or Rheumatoid Arthritis), radiation therapy, chemotherapy, excessive alcohol use, sickle cell disease, decompression sickness, coagulation disorders, Vasculitis, lipid storage disease, and AIDS.

This secondary degeneration is the most feared complication of the initial diagnosis of AVN. The rationale for stem cell therapy with knee AVN is to retard secondary degeneration or promote a healing cascade via a variety of mechanisms.

Knee AVN

Patients are also seeking stem cell therapy in cases of knee AVN as an alternative to knee joint replacement surgery. In fact, stem cell therapy is becoming a more frequent request for patients who wish to avoid all knee surgery, or who have not found the success they desire after already having had knee surgery. These patients are opting for knee stem cell treatment instead.

The possibility of diminished knee pain, improvement in function, walking, daily activities or sports participation all are part of the equation in factoring knee stem cell options. The possibility of avoiding knee replacement surgery is a very frequent consideration, especially for patients with knee AVN.

 Tampa Bay, Florida (727) 462-5582 

Beverly Hills, California (310) 975-7033


Dr. Lox

Whether you are a professional athlete, weekend warrior, or have arthritis from aging, Dr. Lox can help. Dennis M. Lox, M.D. is an internationally renown Sports and Regenerative Medicine specialist. Dr. Lox incorporates Regenerative Medicine techniques such as cell science applications, Platelet Rich Plasma (PRP), and Tissue Engineering aspects, to help patients from around the world with a vast array of problems. Dr. Lox is board certified in Physical Medicine and Rehabilitation. Dr. Lox lectures extensively and has edited two PM&R textbooks, the prestigious A State of the Art Review (Star) on Low Back Pain, and Soft Tissue Injuries: Diagnosis and Treatment. Dennis M. Lox, M.D. maintains an active practice in the Tampa Bay, Florida area, and in Beverly Hills, California.

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Stem Cell Therapy in Clearwater, FL and Beverly Hills, CA

Dr. Lox treats the Tampa Bay Metro Area including Clearwater, St. Petersburg, Tampa , Pinellas Park, Palm Harbor, Orlando and Sarasota as well as the Los Angeles Metro Area including Santa Monica and Beverly Hills.

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Clearwater, Florida Office

2030 Drew St.
Clearwater, FL 33765
(727) 462-5582

Beverly Hills, California Office

450 N Roxbury Dr. #602
Beverly Hills, CA 90210
(310) 975-7033

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